Diabetes distress and depression are independently associated with gastrointestinal symptoms in type 2 diabetes in Bangladesh

Authors: M Kamruzzaman, M Horowitz, W H Polonsky, N J Talley, M A Borg, C K Rayner, K L Jones, C S Marathe

Abstract

Background and aims: Gastrointestinal (GI) symptoms, common in type 2 diabetes (T2D), are typically bothersome, socially embarrassing, and impact negatively on quality of life. They may also contribute to diabetes distress (DD), but this has never been formally evaluated. We aimed to investigate the relationships between GI symptoms, DD and depressive symptoms in a large cohort of individuals with T2D in Bangladesh.

Materials and methods: 1406 unselected T2D individuals (female 58.8%; mean age 51.0 ± 12.5 years) from four diabetes clinics in Bangladesh completed validated questionnaires evaluating GI symptoms (PAGI-SYM), DD (DDS-17) and depressive symptoms (PHQ-9).

Results: 31.1% of participants reported GI symptoms (36.2% females, 23.7% males), while 51.1% had elevated DD and 37.8% depressive symptoms. GI symptoms exhibited independent relationships with both DD and depressive symptoms, and their likelihood was higher among those with DD (OR: 3.6 [2.2-5.6] and with depressive symptoms (OR: 5.9 [3.5-9.9]).

Conclusions: GI symptoms are independently associated with both DD and depressive symptoms in people with T2D in Bangladesh.

Source: https://pubmed.ncbi.nlm.nih.gov/38881382/

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BDI Monthly Events

November 12: BDI hosts the San Diego-wide, monthly case consultation meeting (for mental health professionals working in the field of diabetes). Contact us at [email protected] if you are in the greater San Diego area and would like further information about this program.

November 15: Time for another T1D meet-up! GrownupT1Ds, a wonderful nonprofit here in southern California, which organizes fun social events for adults with type 1 diabetes here in southern California. This next one will be at 2 pm at Brewery X, 3191 E La Palma Ave, Anaheim, CA. This event is free, but space is limited. Please RSVP at www.grownupt1ds.orgmeetings/annual/info

November 7: Dr Guzman (BDI Director of Clinical Education) and Dr Fisher (BDI Director of Research) will lead an adapted DD-ASSIST Program for the clinical team the UCSF Diabetes and Pregnancy Program. The goal of this program is to help the team be able to assess and address pregnancy-related diabetes distress as part of their routine care.